Featured Nobel Articles

Elizabeth Blackburn, a member of the Editorial Board of Aging, won the Nobel Prize in Physiology or Medicine 2009, while being a member of the board. Elizabeth Blackburn co-authored a paper published in the first (inaugural) issue of Aging.
Andrew V. Schally, Nobel Prize Laureate, published his paper in Aging.
Shinya Yamanaka won the Nobel Prize in Physiology and Medicine 2012. Shinya Yamanaka co-authored a paper published in Aging.

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Volume 15, Issue 16

30 August, 2023
pp 7857—8530

About the Cover

The cover features Figure 6 "Dectin-1 stimulation leads to distinct signatures of differentiation" from Kumar et al.

Explore This Issue

Editorials

The effect of age on melanoma incidence and prognosis

John F. Thompson, Gabrielle J. Williams,

https://doi.org/10.18632/aging.204653 pp 7857—7859

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Microvascular contributions to white matter injury in Alzheimer’s disease

Zsolt Bagi, Larry S. Sherman, Stephen A. Back,

https://doi.org/10.18632/aging.204997 pp 7860—7862

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Mitochondria: between aging, frailty and sarcopenia

Annalisa Davin, Riccardo Rocco Ferrari, Orietta Pansarasa,

https://doi.org/10.18632/aging.204998 pp 7863—7865

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Research Papers

Dectin-1 stimulation promotes a distinct inflammatory signature in the setting of HIV-infection and aging

Archit Kumar, Jiawei Wang, Allen Esterly, Chris Radcliffe, Haowen Zhou, Brent Vander Wyk, Heather G. Allore, Sui Tsang, Lydia Barakat, Subhasis Mohanty, Hongyu Zhao, Albert C. Shaw, Heidi J. Zapata,

https://doi.org/10.18632/aging.204927 pp 7866—7908

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Reorganization of pancreas circadian transcriptome with aging

Deepak Sharma, Caitlin R. Wessel, Mahboobeh Mahdavinia, Fabian Preuss, Faraz Bishehsari,

https://doi.org/10.18632/aging.204929 pp 7909—7921

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Copy number variation as a tool for implementing pregnancy as an aging model

Mariana Andrawus, Lital Sharvit, Noga Touitou, Batia Lerrer, Haim Y. Cohen, Gil Atzmon,

https://doi.org/10.18632/aging.204936 pp 7922—7932

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A novel hepatocellular carcinoma-specific mTORC1-related signature for anticipating prognosis and immunotherapy

Erbao Chen, Yuqian Mo, Jing Yi, Jie Liu, Ting Luo, Zheng Li, Zewei Lin, Yibing Hu, Zhilin Zou, Jikui Liu,

https://doi.org/10.18632/aging.204862 pp 7933—7955

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A novel telomere-related gene prognostic signature for survival and drug treatment efficiency prediction in lung adenocarcinoma

Haiming Chen, Weiquan Liang, Weiqiang Zheng, Feilong Li, Xingxi Pan, Yiyu Lu,

https://doi.org/10.18632/aging.204877 pp 7956—7973

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Prognostic significance and mechanisms of CXCL genes in clear cell renal cell carcinoma

Junwen Shen, Rongjiang Wang, Yu Chen, Zhihai Fang, Jianer Tang, Jianxiang Yao, Jianguo Gao, Xiaonong Chen, Xinli Shi,

https://doi.org/10.18632/aging.204922 pp 7974—7996

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HYDIN mutation status as a potential predictor of immune checkpoint inhibitor efficacy in melanoma

Liu Li, Kuang Tianrui, Li Chunlei, Qiu Zhendong, Chen Xiaoyan, Deng Wenhong,

https://doi.org/10.18632/aging.204925 pp 7997—8012

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TNFR2 promotes pancreatic cancer proliferation, migration, and invasion via the NF-κB signaling pathway

Zetian Gao, Qiubo Zhang, Hang Chen, Jiayi Chen, Jingyu Kang, Hang Yu, Yufei Song, Xie Zhang,

https://doi.org/10.18632/aging.204941 pp 8013—8025

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NDUFB11 and NDUFS3 play a role in atherosclerosis and chronic stress

Yin Yang, Jing-Hui Li, Bo-Chen Yao, Qing-Liang Chen, Nan Jiang, Lian-Qun Wang, Zhi-Gang Guo,

https://doi.org/10.18632/aging.204947 pp 8026—8043

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The alleviating effect and mechanism of GLP-1 on ulcerative colitis

Wenrui Wang, Chuan Zhang, Haolong Zhang, Luyao Li, Tingting Fan, Zhenjing Jin,

https://doi.org/10.18632/aging.204953 pp 8044—8060

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Coumarin-chalcone hybrid LM-021 and indole derivative NC009-1 targeting inflammation and oxidative stress to protect BE(2)-M17 cells against α-synuclein toxicity

Pei-Ning Yang, Wan-Ling Chen, Jun-Wei Lee, Chih-Hsin Lin, Yi-Ru Chen, Chung-Yin Lin, Wenwei Lin, Ching-Fa Yao, Yih-Ru Wu, Kuo-Hsuan Chang, Chiung-Mei Chen, Guey-Jen Lee-Chen,

https://doi.org/10.18632/aging.204954 pp 8061—8089

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Identification of immunotherapy biomarkers for improving the clinical outcome of homologous recombination deficiency patients with lung adenocarcinoma

Xiang Zhou, Rongjian Xu, Tong Lu, Ran Xu, Chenghao Wang, Bo Peng, Xiaoyan Chang, Zhiping Shen, Kaiyu Wang, Jiaxin Shi, Jiaying Zhao, Lin-You Zhang,

https://doi.org/10.18632/aging.204957 pp 8090—8112

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Comprehensive characterization of pyroptosis phenotypes with distinct tumor immune profiles in gastric cancer to aid immunotherapy

Kaida Huang, Yubiao Lin, Guoqin Qiu, Shengyu Wang, Lihua Feng, Zhigao Zheng, Yingqin Gao, Xin Fan, Wenhui Zheng, Jianmin Zhuang, Fanghong Luo, Shuitu Feng,

https://doi.org/10.18632/aging.204958 pp 8113—8136

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CEACAM1 as a molecular target in oral cancer

Sai Ma, Zhonghua Wang, Chao Li, Zhenli Liu, Xuan Zhang, Liheng Li, Feng An, Xiaoli Qiao,

https://doi.org/10.18632/aging.204960 pp 8137—8154

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Identified RP2 as a prognostic biomarker for glioma, facilitating glioma pathogenesis mainly via regulating tumor immunity

Yiyang Gong, Yun Ke, Zichuan Yu, Jingying Pan, Xuanrui Zhou, Yike Jiang, Minqin Zhou, Hong Zeng, Xitong Geng, Guowen Hu,

https://doi.org/10.18632/aging.204962 pp 8155—8184

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Construction of stemness gene score by bulk and single-cell transcriptome to characterize the prognosis of breast cancer

Jun Lin, Deyi Feng, Jie Liu, Ye Yang, Xujin Wei, Wenqian Lin, Qun Lin,

https://doi.org/10.18632/aging.204963 pp 8185—8203

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PTPRD mutation is a prognostic biomarker for sensitivity to ICIs treatment in advanced non-small cell lung cancer

Zhixuan Ren, Li Wang, Chaohui Leng,

https://doi.org/10.18632/aging.204964 pp 8204—8219

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Inhibition of VCP modulates NF-κB signaling pathway to suppress multiple myeloma cell proliferation and osteoclast differentiation

Rongfang Wei, Yuhao Cao, Hongjie Wu, Xin Liu, Mingmei Jiang, Xian Luo, Zhendong Deng, Ze Wang, Mengying Ke, Yongqiang Zhu, Siqing Chen, Chunyan Gu, Ye Yang,

https://doi.org/10.18632/aging.204965 pp 8220—8236

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Single-cell RNA sequencing and multiple bioinformatics methods to identify the immunity and ferroptosis-related biomarkers of SARS-CoV-2 infections to ischemic stroke

Xiang Zhao, Qingyu Liang, Hao Li, Zhitao Jing, Dongmei Pei,

https://doi.org/10.18632/aging.204966 pp 8237—8257

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Acetyl-cinobufagin suppresses triple-negative breast cancer progression by inhibiting the STAT3 pathway

Yufeng Qi, Haodong Wu, Tianru Zhu, Zitian Liu, Conghui Liu, Congzhi Yan, Zhixuan Wu, Yiying Xu, Ying Bai, Lehe Yang, Dezhi Cheng, Xiaohua Zhang, Haiyang Zhao, Chengguang Zhao, Xuanxuan Dai,

https://doi.org/10.18632/aging.204967 pp 8258—8274

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Integrative analysis links autophagy to intrauterine adhesion and establishes autophagy-related circRNA-miRNA-mRNA regulatory network

Xiaotong Peng, Yiping Zhu, Tao Wang, Shuo Wang, Jing Sun,

https://doi.org/10.18632/aging.204969 pp 8275—8297

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Gastrodin ameliorates cognitive dysfunction in diabetes by inhibiting PAK2 phosphorylation

Zhi-Hao Mu, Zhi-Min Zhao, Su-Su Yang, Lei Zhou, Yi-Dan Liu, Zhong-Yi Qian, Xin-Jie Liu, Peng-Chao Zhao, Ren-Bo Tang, Jia-Yin Li, Jing-Yao Zeng, Zhi-Hong Yang, Yong-Hua Ruan, Ying Zhang, Yue-Qin Zeng, Ying-Ying Zou,

https://doi.org/10.18632/aging.204970 pp 8298—8314

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miR-100-5p activation of the autophagy response through inhibiting the mTOR pathway and suppression of cerebral infarction progression in mice

Xiaoyun Cao, Xiangjian Zhang, Junmin Chen, Qian Sun, Yufan Sun, Na Lin, Xiaoxia Liu,

https://doi.org/10.18632/aging.204971 pp 8315—8324

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Construction and validation of cuproptosis-related lncRNA prediction signature for bladder cancer and immune infiltration analysis

Hanrong Li, Huiming Jiang, Zhicheng Huang, Zhilin Chen, Nanhui Chen,

https://doi.org/10.18632/aging.204972 pp 8325—8344

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Investigating causal associations among gut microbiota, gut microbiota-derived metabolites, and gestational diabetes mellitus: a bidirectional Mendelian randomization study

Xinrui Wu, Dihui Lin, Qi Li, Jiawang Cai, Houxiang Huang, Tianyu Xiang, Hongzhuan Tan,

https://doi.org/10.18632/aging.204973 pp 8345—8366

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The novel angiogenesis regulator circFAM169A promotes the metastasis of colorectal cancer through the angiopoietin-2 signaling axis

Zhiwei Wu, Fan Zhang, Shaobin Huang, Ming Luo, Kai Yang,

https://doi.org/10.18632/aging.204974 pp 8367—8383

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Prognosis analysis and validation of lipid metabolism-associated lncRNAs and tumor immune microenvironment in bladder cancer

Zhiyong Tan, Shi Fu, Jieming Zuo, Jiansong Wang, Haifeng Wang,

https://doi.org/10.18632/aging.204975 pp 8384—8407

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SART3, regulated by p53, is a biomarker for diagnosis, prognosis and immune infiltration in hepatocellular carcinoma

Jusen Nong, Kejian Yang, Tianman Li, Chenlu Lan, Xin Zhou, Junqi Liu, Haixiang Xie, Jianzhu Luo, Xiwen Liao, Guangzhi Zhu, Tao Peng,

https://doi.org/10.18632/aging.204978 pp 8408—8432

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Catapol reduced the cognitive and mood dysfunctions in post-stroke depression mice via promoting PI3K-mediated adult neurogenesis

Bo Li, Xin Zhou, Lu Zhen, Weiwei Zhang, Jian Lu, Jie Zhou, Huoquan Tang, Huangsuo Wang,

https://doi.org/10.18632/aging.204979 pp 8433—8443

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m⁶A methyltransferase METTL16 mediates immune evasion of colorectal cancer cells via epigenetically regulating PD-L1 expression

Ailei Wang, Yingjie Sun, Xince Wang, Zhaofei Yan, Dongsheng Wang, Li Zeng, Qingge Lu,

https://doi.org/10.18632/aging.204980 pp 8444—8457

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Curcumin alleviates orofacial allodynia and improves cognitive impairment via regulating hippocampal synaptic plasticity in a mouse model of trigeminal neuralgia

Hong-Wei Zhi, Yu-Zhi Jia, Huai-Qian Bo, Hai-Tao Li, Si-Shuo Zhang, Ya-Han Wang, Jie Yang, Ming-Zhe Hu, Hong-Yun Wu, Wen-Qiang Cui, Xiang-Dong Xu,

https://doi.org/10.18632/aging.204984 pp 8458—8470

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Tumor-derived exosomes RNA expression profiling identifies the prognosis, immune characteristics, and treatment in HR+/HER2-breast cancer

Qi Zhou, Jing Wang, Haiping Zhang, Lu Sun, Jingjing Liu, Lingchao Meng, Jingwu Li,

https://doi.org/10.18632/aging.204986 pp 8471—8486

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ZBTB34 is a hepatocellular carcinoma-associated protein with a monopartite nuclear localization signal

Zheng Liu, Di Jin, Xinran Wei, Yue Gao, Xiaodie Gao, Xia Li, Xiujuan Wang, Pingying Wei, Tao Liu,

https://doi.org/10.18632/aging.204987 pp 8487—8500

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Xuebijing injection protects sepsis induced myocardial injury by mediating TLR4/NF-κB/IKKα and JAK2/STAT3 signaling pathways

Xiang-Fei Kang, Xiao-Li Lu, Cheng-Fei Bi, Xiao-Dong Hu, Ying Li, Jin-Kui Li, Li-Shan Yang, Jia Liu, Lei Ma, Jun-Fei Zhang,

https://doi.org/10.18632/aging.204990 pp 8501—8517

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miR-153-3p suppresses the differentiation and proliferation of neural stem cells via targeting GPR55

Xiaolin Dong, Hui Wang, Liping Zhan, Qingyun Li, Yang Li, Gang Wu, Huan Wei, Yanping Li,

https://doi.org/10.18632/aging.204002 pp 8518—8527

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Correction

Correction for: CD229 interacts with RASAL3 to activate RAS/ERK pathway in multiple myeloma proliferation

Zigen Lin, Xiaozhu Tang, Yuhao Cao, Lijin Yang, Mingmei Jiang, Xinying Li, Jie Min, Bing Chen, Ye Yang, Chunyan Gu,

https://doi.org/10.18632/aging.205006 pp 8528—8529

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Retraction

Retraction: Exosomal miRNA-34 from cancer-associated fibroblasts inhibits growth and invasion of gastric cancer cells in vitro and in vivo

Liang Shi, Zhenyong Wang, Xiuchao Geng, Yuhao Zhang, Ziqing Xue,

https://doi.org/10.18632/aging.205020 pp 8530

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