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The cover features Figure 9 "Summary of key findings" from Dipali et al.

Volume 15, Issue 20

31 October, 2023
pp 10814—11693

About the Cover

The cover features Figure 9 "Summary of key findings" from Dipali et al.


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Editorial

Poor communication between ER and mitochondria: a signature of ALS/FTD?

Christopher C.J. Miller, Patricia Gomez-Suaga,
https://doi.org/10.18632/aging.205206 pp 10814—10816
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Research Perspective

Cholinergic centro-cingulate network in Parkinson disease and normal aging

Nicolaas I. Bohnen, Sygrid van der Zee, Roger Albin,
https://doi.org/10.18632/aging.205209 pp 10817—10820
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Priority Research Paper

Proteomic quantification of native and ECM-enriched mouse ovaries reveals an age-dependent fibro-inflammatory signature

Shweta S. Dipali, Christina D. King, Jacob P. Rose, Joanna E. Burdette, Judith Campisi, Birgit Schilling, Francesca E. Duncan,
https://doi.org/10.18632/aging.205190 pp 10821—10855
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Research Papers

Deciphering reproductive aging in women using a NOD/SCID mouse model for distinct physiological ovarian phenotypes

María Marchante, Noelia Ramirez-Martin, Anna Buigues, Jessica Martinez, Nuria Pellicer, Antonio Pellicer, Sonia Herraiz,
https://doi.org/10.18632/aging.205086 pp 10856—10874
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Tissue immunoexpression of IL-6 and IL-18 in aging men with BPH and MetS and their relationship with lipid parameters and gut microbiota-derived short chain fatty acids

Weronika Ratajczak, Maria Laszczyńska, Aleksandra Rył, Barbara Dołęgowska, Olimpia Sipak, Ewa Stachowska, Marcin Słojewski, Anna Lubkowska,
https://doi.org/10.18632/aging.205091 pp 10875—10896
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WNT enhancing signals in pancreatic cancer are transmitted by LGR6

Jing Wang, Dominik T. Koch, Felix O. Hofmann, Daniel Härtwig, Iris Beirith, Klaus Peter Janssen, Alexandr V. Bazhin, Hanno Niess, Jens Werner, Bernhard W. Renz, Matthias Ilmer,
https://doi.org/10.18632/aging.205101 pp 10897—10914
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The Saccharomyces cerevisiae acetyltransferase Gcn5 exerts antagonistic pleiotropic effects on chronological ageing

Kaiqiang Li, Gabriele Mocciaro, Jules L. Griffin, Nianshu Zhang,
https://doi.org/10.18632/aging.205109 pp 10915—10937
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Alcohol consumption and epigenetic age acceleration across human adulthood

Mengyao Wang, Yi Li, Meng Lai, Drew R. Nannini, Lifang Hou, Roby Joehanes, Tianxiao Huan, Daniel Levy, Jiantao Ma, Chunyu Liu,
https://doi.org/10.18632/aging.205153 pp 10938—10971
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Chronic kidney disease causes blood-brain barrier breakdown via urea-activated matrix metalloproteinase-2 and insolubility of tau protein

Hisazumi Matsuki, Shintaro Mandai, Hiroki Shiwaku, Takaaki Koide, Naohiro Takahashi, Tomoki Yanagi, Shunsuke Inaba, Saaya Ida, Tamami Fujiki, Yutaro Mori, Fumiaki Ando, Takayasu Mori, Koichiro Susa, Soichiro Iimori, Eisei Sohara, Hidehiko Takahashi, Shinichi Uchida,
https://doi.org/10.18632/aging.205164 pp 10972—10995
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BTN2A2, a new biomarker and therapeutic target for glioma

Heping Wang, Shanrui Pu, Haitao Xu, Lihong Yang, Lishi Shao, Xi Chen, Xiaobin Huang, Jun Pu,
https://doi.org/10.18632/aging.205039 pp 10996—11011
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A comprehensive prognostic and immunological analysis of telomere-related lncRNAs in kidney renal clear cell carcinoma

Ji Chen, Dong Zhang, Xiangbin Ren, Peng Wang,
https://doi.org/10.18632/aging.205056 pp 11012—11032
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Dysregulated expression of slingshot protein phosphatase 1 (SSH1) disrupts circadian rhythm and WNT signaling associated to hepatocellular carcinoma pathogenesis

Shiue-Wei Lai, Yi-Chiao Cheng, Wen-Chien Huang, Vijesh Kumar Yadav, Iat-Hang Fong, Chi-Tai Yeh, Ching-Kuo Yang, Wei-Hwa Lee, Ming-Yao Chen,
https://doi.org/10.18632/aging.205064 pp 11033—11051
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The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma

Haitao Luo, Kai Huang, Mengqi Cheng, Xiaoyan Long, Xingen Zhu, Miaojing Wu,
https://doi.org/10.18632/aging.205076 pp 11052—11066
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HLA-DPA1 overexpression inhibits cancer progression, reduces resistance to cisplatin, and correlates with increased immune infiltration in lung adenocarcinoma

Ke Shi, Qian-Yun Li, Yun-Qiang Zhang, Huan Huang, Dong-Xiao Ding, Wei-Min Luo, Jun Zhang, Qiang Guo,
https://doi.org/10.18632/aging.205082 pp 11067—11091
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Identification and validation of a cancer-associated fibroblasts-related scoring system to predict prognosis and immune landscape in hepatocellular carcinoma through integrated analysis of single-cell and bulk RNA-sequencing

Lingling Bao, Xuede Zhang, Wenjuan Wang, Bitao Jiang,
https://doi.org/10.18632/aging.205099 pp 11092—11113
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Naked cuticle homolog 1 prevents mouse pulmonary arterial hypertension via inhibition of Wnt/β-catenin and oxidative stress

Shanwu Wei, Lu Lin, Wen Jiang, Jie Chen, Gu Gong, Daming Sui,
https://doi.org/10.18632/aging.205105 pp 11114—11130
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Triptolide inhibits epithelial ovarian tumor growth by blocking the hedgehog/Gli pathway

Lanyan Hu, Mai Gao, Huifu Jiang, Lingling Zhuang, Ying Jiang, Siqi Xie, Hong Zhang, Qian Wang, Qi Chen,
https://doi.org/10.18632/aging.205110 pp 11131—11151
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The novel GLP-1/GIP dual agonist DA3-CH improves rat type 2 diabetes through activating AMPK/ACC signaling pathway

Jing Xu, Peng Chen, Dongzhi Wu, Qiang Zhou, Sijie Chen, Xiang Ding, Hongping Xiong,
https://doi.org/10.18632/aging.205118 pp 11152—11161
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Machine learning developed a PI3K/Akt pathway-related signature for predicting prognosis and drug sensitivity in ovarian cancer

Xiaofang Han, Liu Yang, Hui Tian, Yuanyuan Ji,
https://doi.org/10.18632/aging.205119 pp 11162—11183
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Inhibiting microRNA-200a-3p attenuates pyroptosis via targeting the SIRT1/NF-κB/NLRP3 pathway in H2O2-induced HAEC

Jia Liu, Youyou Yan, Dongdong Zheng, Jifeng Zhang, Junnan Wang,
https://doi.org/10.18632/aging.205121 pp 11184—11200
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Tryptophan metabolism-related gene expression patterns: unveiling prognostic insights and immune landscapes in uveal melanoma

Jing Wang, Tienan Zhao, Bo Li, Wei Wei,
https://doi.org/10.18632/aging.205122 pp 11201—11216
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Identification of cellular senescence-related signature for predicting prognosis and therapeutic response of acute myeloid leukemia

Fangmin Zhong, Yulin Yang, Fangyi Yao, Jing Liu, Xiajing Yu, Xin-Lu Wang, Bo Huang, Xiao-Zhong Wang,
https://doi.org/10.18632/aging.205123 pp 11217—11226
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Electroacupuncture pretreatment protects against anesthesia/surgery-induced cognitive decline by activating CREB via the ERK/MAPK pathway in the hippocampal CA1 region in aged rats

Hongjie Huang, Yanan Li, Xupeng Wang, Qi Zhang, Juan Zhao, Qiujun Wang,
https://doi.org/10.18632/aging.205124 pp 11227—11243
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CDKN2A was a cuproptosis-related gene in regulating chemotherapy resistance by the MAGE-A family in breast cancer: based on artificial intelligence (AI)-constructed pan-cancer risk model

Hong Wan, Xiaowei Yang, Guopeng Sang, Zhifan Ruan, Zichen Ling, Mingzhao Zhang, Chang Liu, Xiangyang Hu, Tao Guo, Juntong He, Defeng Liu, Jing Pei,
https://doi.org/10.18632/aging.205125 pp 11244—11267
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Integrated bulk and scRNA sequence identified anoikis-related diagnostic biomarkers and potential association with immune infiltration in type A aortic dissection

Kexiang Feng, Zhongwei Zhang, Jie Luo, Wenjie Wang, Tianjie Li, Jing Luo, Hongbo Huang,
https://doi.org/10.18632/aging.205126 pp 11268—11285
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STK4 is a prognostic biomarker correlated with immune infiltrates in clear cell renal cell carcinoma

Zi-Yuan Bai, Lu-Shan Peng, Run-Qi Li, Xianchu Peng, Zhe Yang,
https://doi.org/10.18632/aging.205127 pp 11286—11297
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Single-cell landscape and spatial transcriptomic analysis reveals macrophage infiltration and glycolytic metabolism in kidney renal clear cell carcinoma

Chen-Yueh Wen, Jui-Hu Hsiao, Yen-Dun Tony Tzeng, Renin Chang, Yi-Ling Tsang, Chen-Hsin Kuo, Chia-Jung Li,
https://doi.org/10.18632/aging.205128 pp 11298—11312
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Role of NF-κB pathway in kidney renal clear cell carcinoma and its potential therapeutic implications

Jiaao Sun, Feng Chen, Guangzhen Wu,
https://doi.org/10.18632/aging.205129 pp 11313—11330
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Exosome and lipid metabolism-related genes in pancreatic adenocarcinoma: a prognosis analysis

Jia Wu, Yajun Li, Ghulam Nabi, Xin Huang, Xu Zhang, Yuanzhen Wang, Liya Huang,
https://doi.org/10.18632/aging.205130 pp 11331—11368
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Comprehensive analysis of integrin αvβ3/α6β1 in prognosis and immune escape of prostate cancer

Yang Liu, Jia-Xin He, Bo Ji, Jin-Feng Wang, Lu Zhang, Zhong-Qi Pang, Jian-She Wang, Bei-Chen Ding, Ming-Hua Ren,
https://doi.org/10.18632/aging.205131 pp 11369—11388
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Development of an immunogenic cell death prognostic signature for predicting clinical outcome and immune infiltration characterization in stomach adenocarcinoma

Ye Liu, Lijia Zhang, Xue Lei, Xinyu Yin, Songjiang Liu,
https://doi.org/10.18632/aging.205132 pp 11389—11411
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Molecular characterization of ferroptosis in soft tissue sarcoma constructs a prognostic and immunotherapeutic signature through experimental and bioinformatics analyses

Zhi-Qiang Yang, Liang-Yu Guo, Kang-Wen Xiao, Chong Zhang, Min-Hao Wu, Fei-Fei Yan, Lin Cai,
https://doi.org/10.18632/aging.205133 pp 11412—11447
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PPIH gene regulation system and its prognostic significance in hepatocellular carcinoma: a comprehensive analysis

Jun Ye, Yilin Pang, Xunjun Yang, Chuan Zhang, Lei Shi, Zhitao Chen, Guijia Huang, Xianhe Wang, Fangyang Lu,
https://doi.org/10.18632/aging.205134 pp 11448—11470
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The Wnt/β-catenin signaling pathway inhibits osteoporosis by regulating the expression of TERT: an in vivo and in vitro study

Yuanqing Cai, Huijun Sun, Xingyu Song, Jianyu Zhao, Dong Xu, Mozhen Liu,
https://doi.org/10.18632/aging.205136 pp 11471—11488
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Anti-cancer targets and molecular mechanisms of formononetin in treating osteosarcoma based on network pharmacology

Lizhi Chen, Yue Zhou, Zheng Weng, Shuang Liu, Ting Li, Yanfang Wang, Yang Yang, Hongmei Liu, Wenhua Huang,
https://doi.org/10.18632/aging.205139 pp 11489—11507
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Single-cell analysis reveals exosome-associated biomarkers for prognostic prediction and immunotherapy in lung adenocarcinoma

Shengrong Lin, Shengjie Zhou, Xin Han, Yang Yang, Hao Zhou, Xuejiao Chang, Yefeng Zhou, Yuqin Ding, Huihui Lin, Qing Hu,
https://doi.org/10.18632/aging.205140 pp 11508—11531
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Indoxyl sulfate induced frailty in patients with end-stage renal disease by disrupting the PGC-1α–FNDC5 axis

Yi-Chou Hou, Min-Tser Liao, Kuo-Wang Tsai, Cai-Mei Zheng, Hui-Wen Chiu, Kuo-Cheng Lu,
https://doi.org/10.18632/aging.205141 pp 11532—11545
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Icariin improves cognitive impairment by inhibiting ferroptosis of nerve cells

Yang Yang, Yiming Fu, Zhipeng Qin, Hongyan Pei, Liping Zhai, Qiaobing Guan, Shasha Wu, Heping Shen,
https://doi.org/10.18632/aging.205144 pp 11546—11553
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Comprehensive analysis of transcriptome data and experimental identification show that solute carrier 35 member A2 (SLC35A2) is a prognostic marker of colorectal cancer

Yue Wang, Liang Chen, Jing Chen, Zhenzhen Bai, Liyu Cao,
https://doi.org/10.18632/aging.205145 pp 11554—11570
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Metabolic and senescence characteristics associated with the immune microenvironment in non-small cell lung cancer: insights from single-cell RNA sequencing

Hongliang Liao, Zihao Wan, Yaqin Liang, Lin Kang, Renping Wan,
https://doi.org/10.18632/aging.205146 pp 11571—11587
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Immunobiological signatures and the emerging role of SPP1 in predicting tumor heterogeneity, malignancy, and clinical outcomes in stomach adenocarcinoma

Yanan Wu, Lingyu Ren, Yichun Tang, Zhu Zhu, Shifan Liu, Yan Jiang, Siming Zhang, Xiaocan Zhuang, Yuanbiao Chen,
https://doi.org/10.18632/aging.205148 pp 11588—11610
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BCL2A1 is associated with tumor-associated macrophages and unfavorable prognosis in human gliomas

Lun Gao, Zhang Ye, Shu Peng, Pan Lei, Ping Song, Zhiyang Li, Long Zhou, Qiuwei Hua, Li Cheng, Hangyu Wei, Junhui Liu, Qiang Cai,
https://doi.org/10.18632/aging.205149 pp 11611—11638
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Neurovascular protection of alisol A on cerebral ischemia mice through activating the AKT/GSK3β pathway

Huihong Li, Caiyun Zhang, Yangjie Zhou, Yunfei Deng, Xiaoqing Zheng, Xiehua Xue,
https://doi.org/10.18632/aging.205151 pp 11639—11653
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PCMT1 regulates the migration, invasion, and apoptosis of prostate cancer through modulating the PI3K/AKT/GSK-3β pathway

Jiacheng Zhong, Chao Yuan, Lin Liu, Yang Du, Yumin Hui, Zhiyuan Chen, Changhui Diao, Rui Yang, Guiyong Liu, Xiuheng Liu,
https://doi.org/10.18632/aging.205152 pp 11654—11671
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Identification of key circadian rhythm genes in skin aging based on bioinformatics and machine learning

Xiao Xiao, Hao Feng, Yangying Liao, Hua Tang, Lan Li, Ke Li, Feng Hu,
https://doi.org/10.18632/aging.205155 pp 11672—11689
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Corrections

Correction for: ASXL1 promotes adrenocortical carcinoma and is associated with chemoresistance to EDP regimen

Liang Wang, Yinfeng Lyu, Yuqing Li, Kunping Li, Hui Wen, Chenchen Feng, Ning Li,
https://doi.org/10.18632/aging.205255 pp 11690—11691
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Correction for: miR-320 accelerates chronic heart failure with cardiac fibrosis through activation of the IL6/STAT3 axis

Fang Li, Shan-Shan Li, Hui Chen, Jian-Zhi Zhao, Jie Hao, Jin-Ming Liu, Xiu-Guang Zu, Wei Cui,
https://doi.org/10.18632/aging.205256 pp 11692—11693
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Volume 15, Issue 20  
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