Research Paper Volume 15, Issue 20 pp 11654—11671
PCMT1 regulates the migration, invasion, and apoptosis of prostate cancer through modulating the PI3K/AKT/GSK-3β pathway
Figure 6. PI3K/AKT signaling pathway activator 740Y-P affects the protein expression of related factors in siRNA-PCMT1 PCa cells. (A) Protein expression of E-cadherin, N-cadherin, Snail, Bax, Bcl-2, cleaved caspase-3, P-AKT, AKT, P-GSK-3β, and GSK-3β; in PC3 and DU145 cell lines. (B, C) Quantitative analysis of the protein expression levels in PC3 and DU145 cell lines. Data are expressed as mean ± SD of at least three experiments. **P < 0. 01, ***P < 0. 001. Abbreviation: n. s: not significant.