Research Paper Volume 15, Issue 20 pp 11588—11610

Immunobiological signatures and the emerging role of SPP1 in predicting tumor heterogeneity, malignancy, and clinical outcomes in stomach adenocarcinoma

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Figure 5. Construction of the risk signature. (A) Multivariate Cox regression analysis. (B) LASSO regression analysis. (C) Heatmap of clinical correlations, with asterisks representing differences in this clinical trait between high- and low-risk groups. ***p < 0.001; **p < 0.01; *p < 0.05. (D) Clinical correlation analysis of differences in risk scores between different clusters. (E) Sankey diagram linking cluster, risk, and prognosis. (F) Box plot for differential analysis of IRGs in high- and low-risk groups.