Research Paper Volume 15, Issue 20 pp 11588—11610
Immunobiological signatures and the emerging role of SPP1 in predicting tumor heterogeneity, malignancy, and clinical outcomes in stomach adenocarcinoma
Figure 3. Unsupervised clustering analysis based on 12 survival genes. (A) Consensus matrix heat map defining three clusters (K = 3). (B) Unsupervised clustering analysis. For each k, calculate the relative change in the area under the CDF curve compared to k-1. (C) Heatmap based on 12 genes. (D) Survival analysis of clusters showing differences in patients’ prognosis between clusters. (E) GSVA analysis showing differences in different pathways of different clusters. (F) Box plot revealing immune infiltration of different clusters. ***p < 0.001; **p < 0.01; *p < 0.05.