Research Paper Volume 15, Issue 20 pp 11298—11312

Single-cell landscape and spatial transcriptomic analysis reveals macrophage infiltration and glycolytic metabolism in kidney renal clear cell carcinoma

class="figure-viewer-img"

Figure 2. Evaluation of the diagnostic potential of PGAM1 expression in KIRC biopsy specimens. (A) PGAM1 gene expression levels in renal cancer. (B) Comparison of PGAM1 expression between KIRC tumor and non-tumor tissues. Boxplots depicting PGAM1 expression levels across different stages (C), metastasis status (D), and ccRCC subtypes (E) of KIRC. (F) Comparative immunohistochemical analysis of PGAM1 expression in KIRC tissue samples from four different patients based on the Human Protein Atlas. (G) Prognostic significance of PGAM1 mRNA levels for overall survival, as determined using the Kaplan-Meier plotter dataset.