Research Paper Volume 15, Issue 20 pp 11268—11285
Integrated bulk and scRNA sequence identified anoikis-related diagnostic biomarkers and potential association with immune infiltration in type A aortic dissection
Figure 4. Definition and validation of targeted miRNA for diagnostic ARGs. (A, B) Validation of higher expression of diagnostic ARGs in GSE98770 and GSE52093. (C) Global between diagnostic ARGs and predicted miRNAs. (D) The vital regulatory network of common miRNAs to regulate the diagnostic ARGs. (E) Validation of higher expression of diagnostic ARGs in non-code RNA dataset (GSE190635). (F) Validation of the expressional levels of common miRNAs in TAAD based on GSE190635. (G) The heatmap of 28 immune cells’ ssGSEA scores between TAAD and HC cohorts. (H) The boxplot demonstrated the activation of macrophages, monocytes, activated dendritic cells and CD56+ dim NK cells, and the inhabitation of Th1 cells, B cells and CD56+ bright NK cells.