Research Paper Volume 15, Issue 20 pp 11152—11161

The novel GLP-1/GIP dual agonist DA3-CH improves rat type 2 diabetes through activating AMPK/ACC signaling pathway

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Figure 6. Inactivation of AMPK/ACC signaling pathway by Com-C significantly reversed the influence of DA3-CH on fat levels and oxidative stress condition. (A) The level of fasting blood glucose was measured; (B) The HOMA-IR was analyzed; (C) The total cholesterol level in the serum was measured; (D) The triglyceride level in the serum was measured; (E) The SOD level in the serum was measured; (F) The GSH-PX level in the serum was measured. * means p <0.05. n=5 for each group.