Research Paper Volume 15, Issue 20 pp 11052—11066
The HNF4A-CHPF pathway promotes proliferation and invasion through interactions with MAD1L1 in glioma
Figure 6. HNF4A stimulated transcription of CHPF in glioma. (A, B) mRNA and protein expression of CHPF in U87 and U251 cells after HNF4A knockdown. (C, D) ChIP assays were performed in U251 cells using a specific HNF4A antibody (anti-HNF4A) or a control normal IgG (anti-IgG) and detected the binding region on the promoter of CHPF was R1. ns P > 0.05, * P < 0.05, ** P < 0.01, *** P < 0.001.