Research Paper Volume 15, Issue 16 pp 8471—8486

Tumor-derived exosomes RNA expression profiling identifies the prognosis, immune characteristics, and treatment in HR+/HER2-breast cancer

class="figure-viewer-img"

Figure 3. Construction and validation of exosome scores. (C) Kaplan–Meier survival curves of OS according to ES groups in TCGA cohort. (D) ROC curves at 3-, 5-, and 7 years of OS according to ES groups in the TCGA cohort. (E) Forest plots of OS. (F) Kaplan–Meier survival curves of DRFS according to ES groups in the GEO validation set. (G) ROC curves at 3- and 5 years of DRFS according to ES groups in the GEO validation set. ES, exosome score; OS, overall survival; TCGA, The Cancer Genome Atlas; ROC, receiver operating characteristic; AUC, area under the curve; DRFS, distant relapse-free survival; AIC, Akaike information criterion; GEO, Gene Expression Omnibus.