Research Paper Volume 15, Issue 16 pp 8113—8136

Comprehensive characterization of pyroptosis phenotypes with distinct tumor immune profiles in gastric cancer to aid immunotherapy

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Figure 9. Validation of the predictive efficacy of the pyroptosis score for immunotherapeutic responses in two anti-PD-1 cohorts. (A) The fraction of patients with clinical response to anti-PD-1 therapy in high and low pyroptosis score groups from the GSE78220 cohort. (B) Kaplan-Meier curves for patients with high and low pyroptosis scores in the GSE78220 cohort (log-rank test). (C) The fractions of patients who presented therapeutic responses to anti-PD-1 therapy in high and low pyroptosis score groups from the Liu cohort. (D) Kaplan-Meier curves of patients with high and low pyroptosis scores in the Liu cohort (log-rank test). Abbreviations: CR: complete response; PR: partial response; SD: stable disease; PD: progressive disease.