Research Paper Volume 15, Issue 16 pp 8113—8136

Comprehensive characterization of pyroptosis phenotypes with distinct tumor immune profiles in gastric cancer to aid immunotherapy

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Figure 6. Generation of the pyroptosis score and evaluation of its clinical implication in the gastric cancer meta-cohort. (A) Alluvial diagram of pyroptosis phenotypes with different pyroptosis genomic phenotypes, pyroptosis score and survival status. (B) Distribution of pyroptosis score in three pyroptosis phenotypes. (C) Distribution of pyroptosis score in three pyroptosis genomic phenotypes. (D) Kaplan-Meier survival curves for high and low pyroptosis score groups (log-rank test). (E) Distribution of pyroptosis score in different grades (G1-3). (F) Distribution of pyroptosis score in different stages (stage I–IV). (G) Time-independent ROC curves showing the predictive performance of the pyroptosis score, age, gender, grade, and stage in gastric cancer prognosis.