Research Paper Volume 16, Issue 4 pp 3934—3954
Functional enrichment analysis reveals the involvement of DARS2 in multiple biological pathways and its potential as a therapeutic target in esophageal carcinoma
Figure 8. Prediction and construction of the competing endogenous RNA network of DARS2 in ESCA. (A) The Venn diagram illustrates the co-occurrence of two miRNAs in three databases (TarBase v.8, mirDIP, and miRTarBase). (B) The TCGA ESCA dataset showcases the differential expression of the aforementioned two miRNAs. (C) The expression of hsa-miR-30a-5p in tumor samples from the TCGA ESCA dataset is significantly lower than that in normal samples. (D) Potential binding sites between DARS2 and hsa-miR-30a-5p were predicted using the RNAHybrid online tool. (E) The Venn diagram demonstrates the co-occurrence of nine lncRNAs in two databases. (F) The TCGA ESCA cohort presents the differential expression of the aforementioned nine lncRNAs. (G) The expression of DLEU2 in tumor samples from the TCGA ESCA dataset is significantly higher than that in normal samples. (H) Potential binding sites between hsa-miR-30a-5p and DLEU2 were predicted using the RNAHybrid online tool.