Research Paper Volume 16, Issue 4 pp 3837—3855

Dickkopf-1 is an immune infiltration-related prognostic biomarker of head and neck squamous cell carcinoma

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Figure 7. Gene expression, CNV, and mutation feature analysis of DKK1 expression. (A) CNA and mutation-frequency data related to DKK1 expression in different tumor types were accessed from cBioPortal. (B) The alteration frequencies of different mutation types in HNSCC were displayed using the cBioPortal tool. (C) Heatmap showed correlations between DKK1 mRNA expression levels and CNVs, somatic mutations, and DNA methylation in HNSCC, based on information in the UCSC Xena database. (D) A plot showed the relationship between DKK1 mRNA expression and CNAs in the DKK1 gene in HNSCC tumors, as determined using the cBioPortal tool.