Research Paper Volume 16, Issue 4 pp 3790—3802

MUC1 promotes RIF by regulating macrophage ROS-SHP2 signaling pathway to up-regulate inflammatory response and inhibit angiogenesis

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Figure 1. Endometrial immune characteristics of RIF patients. (A) The landscape of infiltrating immune cells in endometrial tissues of RIF patients and fertile controls. (B) The proportion of 22 types of immune cells between RIF patients and fertile controls. (C) The associations of selected hub genes and infiltrating immune cells. (D) GSEA of selected hub genes in RIF samples. *P < 0.05, **P < 0.01, ***P < 0.001, ***P < 0.0001, Abbreviations: ns: no significance; RIF: recurrent implantation failure; GSEA: gene set enrichment analysis.