Research Paper Volume 16, Issue 4 pp 3750—3762

Suppression of cerebral ischemia injury induced blood brain barrier breakdown by dexmedetomidine via promoting CCN1

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Figure 7. Dex suppressed OGD induced increase of HRP permeability and promoting tight junction protein expression in vitro. (A) The expression levels of tight junction proteins in HBMEC were measured; (B) Blood brain barrier in vitro was evaluated with HRP permeability; (C) Cell apoptosis was detected with flow cytometry. *p < 0.05. n = 3.