Research Paper Volume 16, Issue 4 pp 3531—3553

Senescence-related genes analysis in breast cancer reveals the immune microenvironment and implications for immunotherapy

class="figure-viewer-img"

Figure 3. The distribution of the risk scores, outcome status, and gene profiles of the gene signature in the training, testing, all, and GEO cohort were shown. (AL) The risk group successfully predicted the outcomes of the patients in both the training and validation cohorts, with significantly more events found in the high-risk group. (EH) In the 9-gene risk signature, genes ACTC1, WT1, IVL, SHCBP1, and MAEL showed higher expression in the high-risk group. (IL) The survival analysis is based on the prognostic model. (MP) To further test the confidence of the risk model, a survival analysis was performed between the high-risk group and low-risk group among the training cohort, the testing cohort, all cohort, and the GEO cohort.