Research Paper Volume 16, Issue 3 pp 2953—2977

Overexpression of SPP1 is a prognostic indicator of immune infiltration in lung adenocarcinoma

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Figure 7. Impact of SPP1 on immune cell infiltration and distribution in LUAD. (A) Distinct immune clusters observed in different cancer types. (B) Immune landscape data of LUAD from different expression groups of SPP1. (C) Variations in the ratios of 21 different immune cell types between tumor samples with high and low SPP1 expression. (D) A heat map illustrated the spread of these immune-infiltrating cells within the tumor specimens. ns: no statistical significance, *p<0.05, **p<0.01, ***p<0.001.