Research Paper Volume 16, Issue 3 pp 2753—2773

Integrative analysis of single-cell and bulk RNA-sequencing data revealed disulfidptosis genes-based molecular subtypes and a prognostic signature in lung adenocarcinoma

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Figure 9. The distribution of the DRG score in tumor microenvironment. (A) The integration performance of the 11 samples exhibits a high degree of efficacy. (B) tSNE plot showed seven cell types from 37,364 cells. (C) The different expression of hub genes in seven cell clusters. (D) The DRG score exhibited a predominant distribution within the myeloid cellular population. (E) Myeloid cells were classified into alveolar macrophages (Alveolar Mac), dendritic cells (DCs), monocyte macrophages (mo-Mac), and monocytes. (F) Distinctive characteristics of hub genes across four myeloid cell types. (G) DRG score was primarily manifested in mo-MAC.