Research Paper Volume 16, Issue 3 pp 2563—2590
Integrative analysis confirms TPX2 as a novel biomarker for clinical implication, tumor microenvironment, and immunotherapy response across human solid tumors
Figure 9. The relationship between TPX2 expression and tumor microenvironment, TMB, MSI and neoantigens in various cancers from TCGA database. (A) The relationship between TPX2 expression and CAF infiltration using the EPIC, MCPCOUNTEER, XCELL and TIDE algorithms. (B) The relationship between TPX2 expression and immune cell infiltration, immune score, and stomal score. (C) Radar map of association between TPX2 expression and TMB. (D) Radar map of association between TPX2 expression and MSI. (E) Radar map of association between TPX2 expression and neoantigens. *p<0.05, **p<0.01, ***p<0.001.