Research Paper Volume 16, Issue 3 pp 2563—2590
Integrative analysis confirms TPX2 as a novel biomarker for clinical implication, tumor microenvironment, and immunotherapy response across human solid tumors
Figure 3. The association of TPX2 expression and CNV, DNA methylation, protein phosphorylation. (A) The association of CNV and expression of TPX2 mRNA using the GSCA analysis (Left). The association of DNA methylation and expression of TPX2 mRNA using the GSCA analysis (Right). Red dots indicate positive association. Blue dots indicate negative association. (B) The promoter methylation level of TPX2 between primary tumor and normal tissues in different cancer types using the GSCA analysis. (C) The phosphorylation level of TPX2 protein between primary tumor and normal tissues in BRCA and LUAD using CPTAC analysis. p-value < 0.05 was considered statistically significant.