Research Paper Volume 16, Issue 3 pp 2362—2384

Prepared Radix Polygoni Multiflori and emodin alleviate lipid droplet accumulation in nonalcoholic fatty liver disease through MAPK signaling pathway inhibition

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Figure 8. The MAPK activator diprovocim restored the inhibitory effect of emodin on the AMPK signaling pathway. (A) Representative Western blot of SREBP-1, ACC1, FASN, and ACLY. (BE) Western blot analysis. (F) Representative Western blot of SREBP-1, ACC1, FASN, ACLY, and P-P38. (GK) Western blot analysis. (LN) Nile red and Oil red O staining and analysis. *indicates comparison with NC, P < 0.05. A indicates a comparison with FFA Medium, P < 0.05. The white line indicates 50 μm.