Research Paper Volume 16, Issue 3 pp 2340—2361

5-methylcytosine RNA modification regulators-based patterns and features of immune microenvironment in acute myeloid leukemia

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Figure 5. Correlation between DNA methylation status and expression of m5C regulators in acute myeloid leukemia (AML). (A) Correlation between the methylation status and mRNA expression of m5C regulators in AML. (B) Scatterplots showing correlation between methylation status and expression of four representative m5C regulators. (C) Association between overall survival of AML patients and methylation status of m5C regulators. (D) Kaplan–Meier curves showing the overall survival of AML patients with DNMT3A, DNMT3B and TRDMT1 methylation.