Research Paper Volume 16, Issue 3 pp 2161—2180
Integrative analysis of LAG3 immune signature and identification of a LAG3-related genes prognostic signature in kidney renal clear cell carcinoma
Figure 7. Construction and validation of a prognostic model based on LAG3-related genes. Univariate (A) and multivariate (B) Cox regression analysis of LAG3-related genes. (C) Nomogram to predict the 1-year, 3-year, and 5-year OS of KIRC. (D) Riskscore scatterplot, survival status scatterplot, and model gene expression heatmap. (E) Survival curve of high/low-risk score. (F) ROC curves of the prognostic model at 1-year, 3-years, and 5-years. (G) The box plot depicting the immune cell infiltration levels in the high- and low-risk groups. (H) Box plot of immune pathway scores in the high- and low-risk groups. (I) Mountain plots of GSEA for the high- and low-risk groups. (*P < 0.05; **P < 0.01; ***P < 0.001).