Research Paper Volume 16, Issue 2 pp 1938—1951
Long noncoding RNA MEG3 regulates cell proliferation and apoptosis by disrupting microRNA-9-5p-mediated inhibition of NDRG1 in prostate cancer
Figure 5. LncMEG3 serves as a sponge for miR-9-5p in PCa. (A) Schematic of the predicted miR-9-5p binding site on lncMEG3. (B) Luciferase activity of wild type or mutated lncMEG3 in 293T cells after cotransfection with miR-9-5p. (C) RIP assay indicated that lncMEG3 and miR-9-5p may have an interaction. (D) Negative correlation between the expression of miR-9-5p and lncMEG3 in 20 PCa tissues analyzed by qPCR, * P < 0.05.