Research Paper Volume 16, Issue 2 pp 1536—1554

Prognostic characteristics of a six-gene signature based on ssGSEA in sarcoma

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Figure 2. MYC targets V1 and V2 play an important role in overall survival in sarcoma patients. (A) In univariate Cox regression analysis, MYC targets V1 and V2 exhibited the highest prognostic significance for sarcoma patients. (B) Patients who died during follow-up had significantly higher Z-scores for MYC targets V1 than those who survived. (C) In Kaplan-Meier analysis, patients with higher Z-scores for MYC targets V1 exhibited poorer OS. (D) Patients who died during follow-up had significantly higher Z-scores for MYC targets V2 than those who survived. (E) In Kaplan-Meier analysis, patients with higher Z-scores for MYC targets V2 exhibited poorer OS. Abbreviation: OS: overall survival. Asterisks indicate statistical significance at: *p < 0.05 and **p < 0.01.