Research Paper Volume 16, Issue 2 pp 1336—1351

Cisplatin and doxorubicin chemotherapy alters gut microbiota in a murine osteosarcoma model

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Figure 5. Four-group comprehensive analysis of changing trends in gut microbiota. (A) Heatmap of genus-level abundance in each group. (B) Differential genus abundance Top10 boxplot. (C) Differential family abundance Top10 boxplot. Abbreviations: PCoA: principal coordinate analysis; LEfSe: linear discriminant analysis coupled with effect size measurements.