Research Paper Volume 16, Issue 1 pp 820—843
Prognostic implication of a novel lactate score correlating with immunotherapeutic responses in pan-cancer
Figure 1. Genetic and transcriptional alterations of LRGs in 33 cancers. (A) The frequencies of total genetic variations for 15 LRGs from the pathway of GO_BP Lactate Metabolic Process in pan-cancer. Red bars mean copy number amplification, blue bars mean copy number deep deletion, yellow bars mean gene mutation. (B) The frequency of copy number amplification for 15 LRGs in each cancer. The numbers in the boxes refer to the percentage of patients with any gene copy number amplification variant compared to all patients in each cancer. (C) The frequency of copy number deep deletion for 15 LRGs in each cancer. The numbers in the boxes refer to the percentage of patients with any gene copy number amplification variant compared to all patients in each cancer. LRGs: lactate-related genes; GO_BP: gene ontology biological process.