Research Paper Volume 16, Issue 2 pp 1318—1335
Long non-coding RNA MEG3 acts as a suppressor in breast cancer by regulating miR-330/CNN1
Figure 3. Overexpression of lncRNA MEG3 on cell viability, apoptosis, migration and invasion. (A) CCK-8 assay evaluated the effect of lncRNA MEG3 overexpression on cell viability. (B) Flow cytometry evaluated the effect of lncRNA MEG3 overexpression on cell apoptosis. (C) Flow cytometry evaluated the effect of lncRNA MEG3 overexpression on cell cycle. (D) Transwell detected the effect of lncRNA MEG3 overexpression on cell migration (magnification, 200×). (E) Transwell detected the effect of lncRNA MEG3 overexpression on cell invasion (magnification, 200×); **P < 0.01 vs. Blank; ##P < 0.01 vs. lncRNA NC.