Research Paper Volume 16, Issue 2 pp 1249—1275

Disulfidptosis status influences prognosis and therapeutic response in clear cell renal cell carcinoma

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Figure 9. Validation of the expression of the disulfidptosis-related molecules using scRNA-seq data. (A) Following quality control and normalization, (B) detection of highly variable genes across the cells using a volcano plot, the top 10 genes are marked. (C) PCA based on scRNA-seq data from seven ccRCC samples. (D) tSNE algorithm classified cells into 20 clusters. (D) The cell types of the various clusters. (E) In total, 20 cell clusters were annotated into nine cell subtypes using the tSNE algorithm. (F) The expression level of the disulfidptosis-related molecules in each cell subtype.