Research Paper Volume 16, Issue 2 pp 1249—1275

Disulfidptosis status influences prognosis and therapeutic response in clear cell renal cell carcinoma

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Figure 6. Identification of disulfidptosis gene clusters in ccRCC. (A) A color-coded heat map of the consensus matrix for k = 3. (B) Cumulative distribution function (CDF) curve of unsupervised clustering when k = 2–9. (C) Relative changes in area under the CDF curve when k = 2–9. (D) Principal component analysis showed a marked difference in the transcriptome between the three disulfidptosis gene clusters. (E) Kaplan–Meier survival curves of different disulfidptosis gene clusters. (F) Heat map of hub genes and clinicopathological features of patients in the three disulfidptosis gene clusters. (G) Expression of 10 disulfidptosis molecules in the three disulfidptosis gene clusters. *P < 0.05, **P < 0.01, ***P < 0.001.