Research Paper Volume 16, Issue 2 pp 1182—1191
Myeloid-specific knockout of Notch-1 inhibits MyD88- and TRIF-mediated TLR signaling pathways by regulating oxidative stress-SHP2 axis, thus restraining aneurysm progression
Figure 1. Specific deficiency of notch-1 in macrophage suppressed the progression of AAA. (A) representative aortic images with identical magnification and quantitative analysis; (B) two-dimensional B-mode high-resolution ultrasonography and quantitative analysis. N = 9, *P < 0.05, **P < 0.01, apoE-KO/Notch-1MAC-KO group vs. apoE-KO/Notch-1WT group.