Research Paper Volume 16, Issue 2 pp 1128—1144

An enriched environment ameliorates maternal sleep deprivation-induced cognitive impairment in aged mice by improving mitochondrial function via the Sirt1/PGC-1α pathway

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Figure 1. The effects of EE on MSD-induced changes in cognitive performance (n = 8). Escape latency, swim distance and velocity of control (CON) group (AC), males (DF), and females (GI). (J) Percent time spent in the target quadrant. (K) Percent distance swam in the target quadrant. *P < 0.05 and ** P< 0.01 vs. male mice in the CON group; #P < 0.05 and ##P < 0.01 vs. male mice in the MSD group; $P < 0.05 and $$P < 0.01 vs. female mice in the CON group; &P < 0.05 and &&P < 0.01 vs. female mice in the MSD group.