Research Paper Volume 16, Issue 2 pp 1096—1110

TRPV1 modulated NLRP3 inflammasome activation via calcium in experimental subarachnoid hemorrhage

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Figure 2. Effect of TRPV1 on neurological function, brain edema, and neuron injury. (A, B) Neurological function at 24 h post-SAH was evaluated via modified Garcia and beam score. (C) The water content of the left hemisphere at 24 h post-SAH. (DG) The relative protein expression of ZO-1, Occludin, and Claudin-5 at 24 h post-SAH was assessed via western blot. (H, I) The neuron number at 24 h post-SAH was assessed via Nissl stain. *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001. Scale bar = 100 μm.