MiR-203a-3p attenuates apoptosis and pyroptosis of chondrocytes by regulating the MYD88/NF-κB pathway to alleviate osteoarthritis progression

Jiayi Chen; Zhutong Liu; He Sun; Mange Liu; Jiangliang Wang; Chenxiao Zheng; Xuewei Cao

doi:doi:10.18632/aging.205373

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Research Paper Volume 15, Issue 23 pp 14457—14472

MiR-203a-3p attenuates apoptosis and pyroptosis of chondrocytes by regulating the MYD88/NF-κB pathway to alleviate osteoarthritis progression

Figure 8. A schematic diagram illustrating the theory in the current study. MiR-203a-3p inhibited cartilage matrix degradation as well as alleviated apoptosis and pyroptosis in in vitro and in vivo OA models by regulating the MYD88/NF-κB pathway.