Research Paper Volume 16, Issue 1 pp 348—366

SNRPB promotes the progression of hepatocellular carcinoma via regulating cell cycle, oxidative stress, and ferroptosis

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Figure 1. Correlation of SNRPB and the clinicopathological features and survival rates of patients with HCC. (A) mRNA relative expression levels of SNRPB in HCC tissues and paired adjacent tissues acquired from TCGA. (B) mRNA relative expression levels of SNRPB in 30 HCC tissues and 30 paired adjacent tissues. (C) ROC analysis of the diagnosis of SNRPB in HCC patients using data obtained from TCGA. (D) ROC analysis of SNRPB expression in 30 HCC and 30 paired adjacent tissues. (E) Forest plot using univariate and multivariate Cox regression analysis. (F) Nomogram of the overall survival (OS) for patients with HCC (1, 3, and 5 years). (G) Calibration curve of OS at 1, 3 and 5 years. The gray diagonal is the ideal case line and the blue cross represents the result of hierarchical Kaplan-Meier correction for each point. (H) Relationship between OS and SNRPB expression in TCGA. (I) Relationship between OS and SNRPB expression obtained using the Kaplan-Meier Plotter. (J) Relationship between HCC stages and the expression level of SNRPB in TCGA dataset. (K) Relationship between HCC stages and the expression level of SNRPB in ICGC dataset. (L) Relationship between HCC stages and the expression level of SNRPB in 30 HCC tissues.