Research Paper Volume 15, Issue 23 pp 14411—14421

MicroRNA 211-5p inhibits cancer cell proliferation and migration in pancreatic cancer by targeting BMP2

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Figure 1. The expression levels of miR-211-5p in PC tissues and cells. (A) The expression of miR-211-5p was detected by qRT-PCR between PC tissues and corresponding adjacent tissues (n=58, p < 0.001, Wilcoxon signed-rank test). GAPDH was used as a loading control. Tumor represented PC tissues and non-tumor represented corresponding adjacent tissues. (B) Kaplan–Meier survival curve of the relationship between miR-211-5p high and low expression groups and the prognosis of PC patients (n=58, p=0.0002, Log-rank test). (C) The expression of miR-211-5p in HPDEC, PANC-1, AsPC-1, SW1990, BxPC-3 and CFPAC-1 cells analyzed by qRT-PCR. Data represent the mean ± SD of triplicate experiments and were statistically analyzed with Student’s t-test, *p < 0.05, ** p < 0.01.