Research Paper Volume 15, Issue 22 pp 12763—12779

Effects of paternal and chronological age on BEGAIN methylation and its possible role in autism

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Figure 2. Paternal age effect on BEGAIN promoter methylation in male but not in female cord bloods. Scatter plot showing significant negative correlation (Pearson’s r = -0.39; p = 0.01) between paternal age (x-axis in years) and mean methylation of 9 CpGs (y-axis in %) in 43 male FCBs (red dots). There was no paternal age effect (Pearson’s r = 0.04; p = 0.78) in 46 female FCBs (green dots).