Research Paper Volume 16, Issue 3 pp 2061—2076
LncRNA MEG3 inhibits the proliferation and migration abilities of colorectal cancer cells by competitively suppressing MiR-31 and reducing the binding of MiR-31 to target gene SFRP1
Figure 1. MEG3 expression is downregulated in CRC cell lines. (A) The expression of MEG3 in normal human colonic epithelial cells and colorectal cancer cells SW480 was detected using RT-qPCR; (B) The expression of MEG3 was detected by RT-qPCR in the overexpression group and the no-load group; (C) The OD values of the overexpression group and the no-load group at 450 nm were detected using CCK8; (D) Western blotting detected the relative expression of Ki-67 in the expression group and the no-load group. **P<0.01.