Research Paper Volume 15, Issue 23 pp 13776—13798

Figure 3. Non-negative matrix factorization (NMF) subtyping of the training set and functional analysis. (A) Consensus plot showing the classification of patients into two clusters (C1 and C2) using NMF analysis. (B) Kaplan-Meier survival curve comparing the two clusters (C1 and C2). (C) Comparison of StromalScore, ImmuneScore, and ESTIMATEScore of C1 and C2. (D) Heatmap of the two clusters with respect to immune inflammation. (E) Enrichment scores of 29 immune cells in the two clusters. (F) Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis of differentially expressed genes between the two clusters. (G) Gene Ontology (GO) analysis results, classifying the genes into Biological Process (BP), Cellular Component (CC), or Molecular Function (MF) categories.