Research Paper Volume 15, Issue 23 pp 13738—13752

Involvement of RFC3 in tamoxifen resistance in ER-positive breast cancer through the cell cycle

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Figure 10. RFC3 affects the migration of TAM-resistant cells in ER-positive breast cancer. (A, B) Transwell assay showed a significant increase in the number of putative cells in the MCF-7 group with RFC3 overexpression compared to the control group. (C, D) Transwell experiments showed that the number of effaced cells was significantly reduced in the MCF-7R group with RFC3 knockdown compared to the control group.