Research Paper Volume 15, Issue 23 pp 13710—13737

Figure 10. Differential expression and enrichment analysis of high and low SDC1 expression groups. (A) Volcano plots show the differential gene expression between SDC1 high expression and SDC1 low expression groups using fold-change values and adjusted p-values. (B) Heatmap showing differential gene expression (only 50 genes were displayed due to a large number of genes). (C–F) KEGG and GO analyses revealed the signaling pathways associated with up-regulated and down-regulated genes in the SDC1 high/low expressed groups. An enriched pathway is considered when p < 0.05 or FDR <0.05.