Research Paper Volume 15, Issue 22 pp 12738—12748
Contribution of membrane raft redox signalling to visfatin-induced inflammasome activation and podocyte injury
Figure 6. Inhibition of NADPH and inflammasome attenuates the visfatin-induced cell permeability in podocytes. Values are arithmetic means ± SEM (n = 5 − 8 each group) of cell permeability in podocytes with visfatin in the presence of inhibitors of MR aggregation (MCD), NADPH oxidase inhibitor (DPI) or caspase-1 inhibitor, WEHD. Abbreviations: Ctrl: Control; Vis: Visfatin; DPI: diphenyleneiodonium; MCD: methyl-β-cyclodextrin. *P < 0.05 vs. control; #P < 0.05 vs. visfatin.