Atorvastatin mitigates memory deficits and brain monocyte infiltration in chronic hypercholesterolemia

Fengchao Gong; Qian Shi; Xiaojie Mou; Kang Wang; Qianqian Wang; Haitao Wang

doi:doi:10.18632/aging.205217

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Research Paper Volume 15, Issue 23 pp 13669—13679

Atorvastatin mitigates memory deficits and brain monocyte infiltration in chronic hypercholesterolemia

Figure 6. Atorvastatin restored the expression of tight junction proteins in the cortex of aged ApoE^-/- mice. (A) mRNA of ZO-1 and occludin was measured by RT-PCR; (B) Protein of ZO-1 and occludin was measured using immunostaining (*, P<0.05 vs. vehicle; #, P<0.05 vs. ApoE^-/- mice group).