Research Paper Volume 15, Issue 22 pp 12982—12997

Multi-omics analysis of the oncogenic role of optic atrophy 1 in human cancer

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Figure 7. Enrichment analysis of OPA1-related genes. (A) OPA1-binding proteins analyzed by STRING. (B) Expression correlation between OPA1 and the selected top 100 correlated genes including PAK2, KPNA4, KPNA1, FYTTD1, and CPSF2. (C) The corresponding heatmap of PAK2, KPNA4, KPNA1, FYTTD1, and CPSF2 in different cancer types. (D) The intersection analysis of genes corrected and interacted with OPA1. (E) KEGG pathway analysis of OPA1 the genes correlated and interacted. (F) GO analysis of OPA1 and the corrected and interacted genes.