Research Paper Volume 15, Issue 22 pp 12794—12816

Identification of mitochondrial-related signature and molecular subtype for the prognosis of osteosarcoma

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Figure 2. Clustering based on NMF. (A) The heatmaps of differentially expressed mitochondrial genes. (B) The cophenetic correlation coefficient is used to reflect the stability of the cluster obtained from NMF. (C) RSS is used to reflect the clustering performance of the model. (D) Consensus map clustered via the NMF algorithm. (E) Kaplan–Meier curve analysis for the two subtypes. (F, G) Immune scores of cells of the tumor microenvironment (TME) showing significant differences.