Research Paper Volume 15, Issue 15 pp 7709—7726

Inhibition of BACE1 attenuates microglia-induced neuroinflammation after intracerebral hemorrhage by suppressing STAT3 activation

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Figure 3. BACE1 correlated with microglial neuroinflammation and erythrophagocytosis. (A, B) Quantification of pro- or anti-inflammatory cytokine gene expression is shown in the bar graphs, with data from at least 5 mice at 3 days post-ICH. Data are shown as the relative change compared to the sham group, *P < 0.05 and **P < 0.01. (C) Flow cytometry histogram of fluorescently labeled erythrocytes in microglia/macrophages. (D) Quantification of the erythrophagocytosis population of microglia in the indicated treated mice at Day 3 after ICH. n = 5 per group. **P < 0.01.