Research Paper Volume 15, Issue 15 pp 7673—7688
Emodin attenuates diabetic kidney disease by inhibiting ferroptosis via upregulating Nrf2 expression
Figure 7. Emodin attenuated ferroptosis related marker in rats with DN. Immunohistochemical staining (A, 200× magnification) as well as semi-quantification (B) of AT1 and CTGF. The mRNA expression of ferroptosis related indicators in Emodin treated group (C–F). The concentration of iron content, GSH, MDA and 4-HNE (G–J). *P < 0.05, **P < 0.01 vs. model group.