Research Paper Volume 15, Issue 15 pp 7673—7688
Emodin attenuates diabetic kidney disease by inhibiting ferroptosis via upregulating Nrf2 expression
Figure 2. Emodin attenuated DM related renal injury by inhibiting ferroptosis. The blood glucose levels and body weight were monitored at different intervention time (A, B). The measurement of renal function related indicators (C–F). HE and Masson staining (G) 200× magnification) as well as semi-quantitative analysis of glomerular area (H–J) of renal tissues in each group. The occurrence ferroptosis aggravated the progression of DN (K). *P < 0.05, **P < 0.01 vs. normal group, #P < 0.05, ##P < 0.01 vs. model group.