Research Paper Volume 15, Issue 15 pp 7440—7450

hsa_circ_0010889 downregulation inhibits malignant glioma progression by modulating the miR-590-5p/SATB1 axis

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Figure 5. Overexpression of SATB1 or inhibition of miR-590-5p reversed glioma cell proliferation and migration after silencing hsa_circ_0010889. (AD) EdU detection showing the proliferative ability of LN229 and U251 cells. The data are expressed as the mean ± SD. *P < 0.05, ***P < 0.001 vs. NC. ###P < 0.001 vs. si-hsa_circ_0010889. (EH) Transwell detection showing migration of LN229 and U251 cells. The data are expressed as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001 vs. NC. ###P < 0.001 vs. si-hsa_circ_0010889. (I, J) Western blot results showing the expression of E-cadherin and N-cadherin.